Hevia Group - Publications

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2018

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118.    Exploiting Synergistic Effects in Organozinc Chemistry for Direct Stereoselective C-Glycosylation Reactions at Room Temperature

     A. Hernán-Gómez, S. A. Orr, M. Uzelac,  A. R. Kennedy,  S. Barroso, X. Jusseau, S. Lemaire, V. Farina, E. Hevia

    Angew. Chem. Int. Ed, 2018, accepted article (Very Important Paper)

    https://onlinelibrary.wiley.com/doi/abs/10.1002/anie.201805758

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117.    Molecular Manipulations of a Utility Nitrogen Heterocyclic Carbene by Sodium Magnesiate Complexes and Transmetallation Chemistry with Gold Complexes

A. Hernán-Gómez, M. Uzelac, S. E. Baillie, D. R. Armstrong, A. R. Kennedy, M. A. Fuentes, E. Hevia

Chem. Eur. J. 2018, accepted article.

https://doi.org/10.1002/chem.201802008

 

116.    Donor-influenced structure-activity correlations in stoichiometric and catalytic reactions of lithium monoamido-monohydrido-dialkylaluminates

R. E. Mulvey, J. Okuda, L. E. Lemmerz, R. McLellan, N. R. Judge, A. R. Kennedy, S. Orr, M. Uzelac, E. Hevia, S. D.Robertson

Chem. Eur. J. 2018, accepted article.

https://doi.org/10.1002/chem.201801541

 

115.    Polar organometallic strategies for regioselective C–H metallation of N-heterocyclic carbenes

M. Uzelac, E. Hevia

Chem. Commun. 2018, 54, 2455

DOI:10.1039/C8CC00049B

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114.    Lithium diamidodihydridoaluminates: bimetallic cooperativity in catalytic hydroboration and metallation applications

V. A. Pollard, S. A. Orr, R. McLellan, A. R. Kennedy, E. Hevia, R. E. Mulvey

Chem. Commun. 2018, 54, 1233

DOI:10.1039/C7CC08214B

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113.    Introducing Glycerol as a Sustainable Solvent to Organolithium Chemistry: Ultrafast Chemoselective Addition of Aryllithium Reagents to Nitriles under Air and at Ambient 

        Temperature

M. J. Rodriguez-Alvarez, J. Garcia-Alvarez, M. Uzelac, M. Fairley, C. T. O’Hara, E. Hevia

Chem. Eur. J. 2018, 24, 1720

https://doi.org/10.1002/chem.201705577

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112.    Utilising Sodium‐Mediated Ferration for Regioselective Functionalisation of Fluoroarenes via C−H and C−F Bond Activations

L. C. H. Maddock, T. Nixon, A. R. Kennedy, M. R. Probet, W. Clegg, E. Hevia

Angew. Chem. Int. Ed. 2018, 57, 187.

https://doi.org/10.1002/anie.201709750

 

2017

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111.    Ligand-induced reactivity of -diketiminate magnesium complexes for regioselective functionalization of fluoroarenes via C–H or C–F bond activations

L. Davin, R. McLellan, A. R. Kennedy, E. Hevia

Chem. Commun., 2017,Advance Article

http://dx.doi.org/10.1039/C7CC07193K

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110.    LiTMP Trans-Metal-Trapping of Fluorinated Aromatic Molecules: A Comparative Study of Aluminum and Gallium Carbanion Traps

R. McLellan, M. Uzelac, A. R. Kennedy, E. Hevia, R. E. Mulvey

Angew. Chem. Int Ed, 2017, 56, 9566

DOI: 10.1002/anie.201706064

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109.    Trans-metal-trapping meets Frustated-Lewis-Pair Chemistry: Ga(CH2SiMe3)3 Induced C-H Functionalizations

M. Uzelac, A. R. Kennedy, E. Hevia

Inorg. Chem. 2017, manuscript accepted (Forum Article)

DOI: 10.1021/acs.inorgchem.7b00549

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108.    C-N bond activation and ring opening of a saturated N heterocyclic carbene via lateral alkali-metal-mediated metallation (AMMM)

A. Hernán-Gómez, A. R. Kennedy, E. Hevia

Angew. Chem. Int Ed, 2017, 56, 6632.

https://doi.org/10.1002/anie.201702246

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107.    Synthetic, Structural and Magnetic Implications of Introducing 2,2’-Dipyridylamide to Sodium-Ferrate Complexes 

L. C. H. Maddock, I. Borilovic, J. McIntyre, A. R. Kennedy, G. Aromí, E. Hevia

Dalton Trans. 2017, advanced article

DOI: 10.1039/C7DT01319A

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106.    Regioselective magnesiation of N-heterocyclic molecules: securing insecure cyclic anions by a β-diketiminate-magnesium clamp

L. Davin, R. McLellan, A. Hernán-Gómez, W. Clegg, A. R. Kennedy, M. Mertens, I. Stepek, E.Hevia

Chem. Commun., 2017,53, 3653

DOI: 10.1039/C6CC09675A

 

2016

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105.    Exploiting Deep Eutectic Solvents and Organolithium Reagent Partnerships: Chemoselective Ultrafast Addition to Imines and Quinolines Under Aerobic Ambient 

       Temperature Conditions

C. Vidal, J. García-Álvarez, A. Hernán-Gómez, A. R. Kennedy, E. Hevia

Angew. Chem. Int. Ed. 2016, 55, 16145 (Highlighted in Chemistry World, https:// www.chemistryworld.com/news/chicken-feed-and-food-ingredients-tame-organolithium-chemistry/2500093.article)

DOI: 10.1002/anie.201609929

 

104.    Structural and Mechanistic Insights into s-Block Bimetallic Catalysis: Sodium Magnesiate-Catalyzed Guanylation of Amines

M. De Tullio, A. Hernán-Gómez, Z. Livingstone, W. Clegg, A. R. Kennedy, R. W. Harrington, A. Antiñolo, A. Martínez, F. Carrillo-Hermosilla, E. Hevia

Chem. Eur. J. 2016, 22, 17646

DOI: 10.1002/chem.201602906

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103.    Heavier alkali-metal gallates as platforms for accessing functionalized abnormal NHC carbene-gallium complexes

M. Uzelac, A. R. Kennedy, A. Hernán-Gómez, M. A. Fuentes, E. Hevia

Z. Anorg. Allg. Chem., 2016, 642, 1241 (Invited contribution to special issue on N-Heterocyclic Carbenes)

DOI: 10.1002/zaac.201600310

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102.    Understanding the subtleties of frustrated Lewis pair activation of carbonyl compounds by N-Heterocyclic carbene/alkyl gallium pairings

M. Uzelac, D. R. Armstrong, A. R. Kennedy, E. Hevia

Chem. Eur. J. 2016, 22, 15826

DOI: 10.1002/chem.201603597

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101.    Synthesis, structure and solution studies on mixed aryl/alkyl lithium zincates

A. J. Roberts, A. R. Kennedy, R. McLellan, S. D. Robertson, E. Hevia

Eur. J. Inorg. Chem., 2016: 4752

DOI: 10.1002/ejic.201601020

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100.    Transforming LiTMP Lithiation of Challenging Diazines through Gallium Alkyl Trans-Metal-Trapping

M. Uzelac, A. R. Kennedy, E. Hevia, R. E. Mulvey

Angew. Chem. Int. Ed. 2016, 55, 13147

DOI: 10.1002/anie.201607284

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99.    Structural and Magnetic Diversity in Alkali-Metal Manganate Chemistry: Evaluating Donor and Alkali-Metal Effects in Co-complexation Processes

M. Uzelac, I. Borilovic, M. Amores, T. Cadenbach, A. R. Kennedy, G. Aromí, and E. Hevia

Chem. Eur. J. 2016, 22, 4843 (VIP Paper)

DOI: 10.1002/chem.201504956

 

98.    Assessing the reactivity of sodium alkyl-magnesiates towards quinoxaline:single elctron transfer (SET) vs. nucleophilic alkylation processes

Z. Livingstone, A. Hernán-Gómez, S. E. Baillie, D. R. Armstrong, L. M. Carrella, W. Clegg, R. W. Harrington, A. R. Kennedy, E. Rentschler and E. Hevia 

Dalton Trans., 2016, Advance Article

DOI: 10.1039/C5DT04044B 

 

2015

 

97.    Alkali-Metal-Mediated Magnesiations of an N-Heterocyclic Carbene: Normal, Abnormal, and “Paranormal” Reactivity in a Single Tritopic Molecule

A. Martínez-Martínez, M. A. Fuentes, A. Hernán-Gómez, E. Hevia, A. R. Kennedy, R. E. Mulvey, C.T.O'Hara

Angew. Chem. Int. Ed. 2015, 54, 14075

DOI: 10.1002/anie.201507586 

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96.    Reactivity of Polar Organometallic Compounds in Unconventional Reaction Media: Challenges and Opportunities

J. Garcia-Alvarez, E. Hevia, V. Capriati

Eur. J. Org. Chem. 2015, 6779.

DOI: 10.1002/ejoc.201590088 

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95.    Accessing Sodium Ferrate Complexes Containing Neutral and Anionic N-Heterocyclic Carbene Ligands: Structural, Synthetic, and Magnetic Insights

L. C. H. Maddock, T. Cadenbach, A. R. Kennedy, I. Borilovic, G. Aromí, E. Hevia

Inorg. Chem. 2015, 54, 9201.

DOI:  10.1021/acs.inorgchem.5b01638

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94.    Rational synthesis of normal, abnormal and anionic NHC–gallium alkyl complexes: structural, stability and isomerization insights

M. Uzelac, A. Hernán-Gómez, D. R. Armstrong, A. R. Kennedy, E. Hevia

Chem. Sci. 2015, 6, 5719.

DOI: 10.1039/C5SC02086G  

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93.    Zincate-Mediated Arylation Reactions of Acridine: Pre- and Postarylation Structural Insights

A. Hernan-Gomez, E. Herd, M. Uzelac, T. Cadenbach, A. R. Kennedy, I. Borilovic, G. Aromi, E. Hevia

Organometallics, 2015, 34, 2614.

DOI: 10.1021/om501251q

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92.     Structurally Defined Zincated and Aluminated Complexes of Ferrocene Made by Alkali-Metal Synergistic Syntheses

W. Clegg, E. Crosbie, S. H. Dale-Black, E. Hevia, G. W. Honeyman, A. R. Kennedy, R. E. Mulvey, D. L. Ramsay, S. D. Robertson

Organometallics, 2015, 34, 2580.

DOI: 10.1021/om5012352 

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91.    Two alternative approaches to access mixed hydride-amido zinc complexes: synthetic, structural and solution implications

A. J. Roberts, W. Clegg, A. R. Kennedy, M. Probert, S. D. Robertson, E. Hevia

Dalton Trans. 2015, 44, 8169.

DOI: 10.1039/C5DT00312A  

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2014

 

90.    Introducing Deep Eutectic Solvents to Polar Organometallic Chemistry: Chemoselective Addition of Organolithium and Grignard Reagents to Ketones in Air

C. Vidal, J. Garcia-Alvarez, A. Hernan-Gomez, A. R. Kennedy, E. Hevia

Angew. Chem. Int. Ed. 2014, 53, 5969.

DOI: 10.1002/anie.201400889

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89.    Potassium-alkyl magnesiates: synthesis, structures and Mg-H exchange applications of aromatic and heterocyclic substrates

S. E. Baillie, T. Bluemke, W. Clegg, A. R. Kenedy, J. Klett, L. Russo, M. de Tullio, E. Hevia,

Chem. Commun. 2014, 50, 12859.

DOI: 10.1039/C4CC05305B 

 

88.    New supramolecular assemblies in heterobimetallic chemistry: synthesis of a homologous series of unsolvated alkali-metal zincates

D. R. Armstrong, H. S. Emerson, A. Hernan-Gomez, A. R. Kennedy, E. Hevia

Dalton Trans. 2014, 43, 14229.

DOI: 10.1039/C4DT01131G

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87.    Structural and reactivity insights in Mg Zn hybrid chemistry: Zn-I exchange and Pd-catalysed cross-coupling applications of aromatic substrates

T. D. Bluemke, W. Clegg, P. Garcia-Alvarez, K. Koszinowski, M. D. Call, L. Russo, E. Hevia,

Chem. Sci. 2014, 5, 3552.

DOI: 10.1039/C4SC01263A

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86.    TMP (2,2,6,6-tetramethylpiperidide)-aluminate bases: lithium-mediated alumination or lithiation alkylaluminium-trapping reagents?

D. R. Armstrong, E. Crosbie, E. Hevia, R. E. Mulvey, D. L. Ramsay, S. D. Robertson

Chem. Sci. 2014, 5, 3031.

DOI: 10.1039/C4SC01108B

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85.    Organozinc Pivalate Reagents: Segregation, Solubility, Stabilization, and Structural Insights,

A. Hernan-Gomez, E. Herd, E. Hevia, A. R. Kennedy, P. Knochel, K. Koszinowski, S.M. Manolikakes, R. E. Mulvey, C. Schnegelsberg

Angew. Chem. Int. Ed. 2014, 53, 2706.

DOI: 10.1002/anie.201309841

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84.    Probing the metallating ability of a polybasic sodium alkylmagnesiate supported by a bulkybis(amido) ligand: deprotomagnesiation reactions of nitrogen-based aromatic substrates

D. R. Armstrong, W. Clegg, A. Hernan-Gomez, A. R. Kennedy, Z. Livingstone, S. D. Robertson, L. Russo, E. Hevia

Dalton Trans, 2014, 43, 4361 (Invited contribution to themed issue New Talent: Europe)

DOI: 10.1039/C3DT52639A 

 

2013

 

83.    Donor-Activated Lithiation and Sodiation of Trifluoromethylbenzene: Structural, Spectroscopic, and Theoretical Insights

J. A. Garden, D. R. Armstrong, W. Clegg, J. Garcia-Alvarez, E. Hevia, A. R. Kennedy, R. E. Mulvey, S. D. Robertson, L. Russo

Organometallics, 2013, 32, 5481.

DOI: 10.1021/om4007664 

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82.    Alkali-metal-mediated zincation (AMMZn) meets N-heterocyclic carbene(NHC) chemistry: Zn–H exchange reactions and structural authentication of a dinuclear Au(I) complex with a NHC anion

D. R. Armstrong, S. E. Baillie, V. L. Blair, N. G. Chabloz, J. Diez, J. Garcia-Alvarez, A. R. Kennedy, S. D. Robertson, E. Hevia

Chem. Sci. 2013, 4, 4259.

DOI: 10.1039/C3SC52101J 

 

81.    Concealed Cyclotrimeric Polymorph of Lithium 2,2,6,6-Tetramethylpiperidide Unconcealed: X-Ray Crystallographic and NMR Spectroscopic Studies

E. Hevia, A. R. Kennedy, R. E. Mulvey, D. L. Ramsay, S. D. Robertson

Chem. Eur. J. 2013, 19, 14069.

DOI: 10.1002/chem.201302709 

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80.    Developing Catalytic Applications of Cooperative Bimetallics: Competitive Hydroamination Trimerization Reactions of Isocyanates Catalysed by Sodium Magnesiates

A. Hernán-Gómez, T. D. Bradley, A. R. Kennedy, Z. Livingstone, S. D. Robertson, E. Hevia,

Chem. Commun. 2013, 49, 8659.

DOI: 10.1039/C3CC45167D 

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79.    Isomeric and chemical consequences of the direct magnesiation of 1,3-benzoazoles using diketiminate-stabilized magnesium bases

S. E. Baillie, V. L. Blair, T. Bradley, W. Clegg, J. Cowan, R. Harrington, A.  Hernan-Gomez, A. R. Kennedy, Z. Livingstone, E. Hevia

Chem. Sci. 2013, 4, 1895.

DOI: 10.1039/C3SC22326D 

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78.    Co-complexation Syntheses, Structural Characterization, and DFT studies of a novel series of Polymeric Alkali-Metal Tetraorganogallates

D. R. Armstrong, E. Brammer, T. Cadenbach, E. Hevia, A. R. Kennedy

Organometallics, 2013, 32, 480.

DOI: 10.1021/om3009469

 

2012

 

77.    Synthesis, structural elucidation, and diffusion-ordered NMR studies of homoleptic alkyllithium magnesiates: donor-controlled structural variations in mixed-metal chemistry

S. D. Baillie, W. Clegg, P. Garcia-Alvarez, E. Hevia, A. R. Kennedy, J. Klett, L. Russo

Organometallics, 2012, 31, 5131-5142.

DOI: 10.1021/om300477m

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76.    Accessing low denticity coordination modes of a high denticity tripodal ligand to complete its coordinative repertoire

T. Cadenbach, E. Hevia, A. R. Kenendy, R. E. Mulvey, J. A. Pickrell, S. D. Robertson

Dalton Transactions, 2012, 41,10141-10144.

DOI: 10.1039/C2DT31061A

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75.    New Lithium-Zincate Approaches for the Selective Functionalisation of Pyrazine: Direct Dideprotozincation vs Nucleophilic Alkylation

S. E. Baillie, V. L. Blair, D. C. Blakemore, D. Hay, E. Hevia, A. R. Kenendy, D. C. Pryde

Chem. Commun. 2012, 48, 1985-1987.

DOI: 10.1039/C2CC16959B 

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74.    Assessing the reactivity of sodium zincate [(TMEDA)Na(TMP)ZntBu2] towards benzoylferrocene: deprotonative metalation vs alkylation reactions

E. Hevia, A. R. Kennedy, M. D. McCall

Dalton Trans 2012, 41, 98-103

DOI: 10.1039/C1DT11465D 

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2011

 

73.    Meta-metallation of N,N-dimethylaniline: Contrasting direct sodium-mediated-zincation with indirect sodiation-dialkylzinc co-complexation

D. R. Armstrong, L. Balloch, E. Hevia, A. R. Kennedy, R. E. Mulvey, C. T. O’Hara, S. D. Robertson

Belstein J. Org. Chem. 2011, 7, 1234-1248.

DOI: 10.3762/bjoc.7.144

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72.    Magnesium-Mediated Benzothiazole Activation: a Room Temperature Cascade of C-H Deprotonation, C-C Coupling, Ring-Opening and Nucleophilic Addition Reactions

V. L. Blair, W. Clegg, A. R. Kennedy, Z. Livingstone, L. Russo, E. Hevia

Angew. Chem. Int. Ed. 2011, 50, 9857-9860.

DOI: 10.1002/ange.201103275 

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71.    A record-breaking Magnesium-Hydride Molecular Cluster: Implications for hydrogen storage

E. Hevia, R. E.Mulvey

Angew. Chem. Int. Ed. 2011, 50, 9242-9243.

DOI: 10.1002/anie.201102978

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70.    Split Personality of Lithium Chloride: Recent Salt Effects in Organometallic Recipes

E. Hevia, R. E. Mulvey

Angew. Chem. Int. Ed. 2011, 50, 6448-6450.     

DOI: 10.1002/anie.201102054 

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69.    Alkali-metal mediated zincation of N-heterocyclic substrates using the lithium zincate complex, (THF)Li(TMP)Zn(tBu)2 and applications in in situ cross-coupling reactions

V. L. Blair, D. C. Blakemore, D. Hay, E. Hevia, D. C. Pryde

Tet. Lett. 2011, 52, 4590-4594.

DOI: 10.1016/j.tetlet.2011.06.090

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68.    A New Polymeric alkyl/alkoxide magnesium-sodium inverse crown complex

S. E. Baillie, V. L. Blair, E. Hevia, A. R. Kennedy

Act Cryst., 2011, C67, m249-m251.

DOI: 10.1107/S0108270111023134 

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67.    Expanding Mg-Zn hybrid chemistry: Inorganic salt effects in addition reactions of organozinc reagents to trifluoromethyl acetophenone and implications for a synergistic lithium-magnesium-zinc activation

D. R. Armstrong, W. Clegg, P. García-Alvarez, M. D. McCall, A. R. Kennedy, L. Russo, E. Hevia

Chem. Eur. J, 2011 17, 8333-8341.

DOI: 10.1002/chem.201100866 

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66.    Shedding New Light on ZnCl2-Mediated Addition Reactions of Grignard Reagents to Ketones: Structural Authentication of Key Intermediates and Diffusion-Ordered NMR Studies

D. R. Armstrong, W. Clegg, P. García-Alvarez, E. Hevia, M. D. McCall, L. Nuttall, A. R. Kennedy, L. Russo

Chem. Eur. J, 2011, 17, 4470.

DOI: 10.1002/chem.201002544 

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65.    Synthesis and Characterization of an Infinite Sheet of Metal-Alkyl Bonds: Unfolding the Elusive     Structure of an     Unsolvated Alkali-Metal Trisalkylmagnesiate

S. E. Baillie, W. Clegg, P. Garcia-Alvarez, E. Hevia, A. R. Kennedy, J. Klett, L. Russo

Chem. Commun, 2011, 47, 388-390.

DOI: 10.1039/C0CC02164D

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2010

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64.    Structural Basis for Regioisomerization in the Alkali-Metal-Mediated Zincation (AMMZn) of Trifluoromethyl Benzene by Isolation of Kinetic and Thermodynamic Intermediates

D. R. Armstrong,.V. L. Blair, W. Clegg, S. H. Dale, J. García-Alvarez, E. Hevia, G. W. Honeyman, R. E. Mulvey, L. Russo

J. Am. Chem. Soc. 2010, 132, 9480-9487.

DOI: 10.1021/ja1038598 

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63.    Exposing the Hidden Complexity of Stoichiometric and Catalytic Metathesis Reactions by  Elucidation of Mg-Zn Hybrids

J. Z. Chua, P. García-Álvarez, E. Hevia, A. R. Kennedy, M. D. McCall

Proc. Natl. Acad. Sci. USA, 2010, 107, 5294-5299.

DOI: 10.1073/pnas.0913307107

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62.    New Insights into Addition Reactions of Dialkylzinc Reagents to Trifluoromethyl Ketones: Structural Authentication of a -hydride Elimination Product Containing a Tetranuclear Zinc Chain

E. Hevia, A. R. Kennedy, J. Klett, Z. Livingstone, M. D. McCall

Dalton Trans, 2010, 39, 520-526.

DOI: 10.1039/B911818G

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2009

 

61.    Closer Insight into the Reactivity of TMP-dialkyl Zincates in Directed ortho-Zincation of Anisole: Experimental Evidence of Amido Basicity and Structural Elucidation of Key Reaction Intermediates

W. Clegg, B. Conway, E. Hevia, M. D. McCall, L. Russo, R. E. Mulvey

J. Am. Chem. Soc. 2009, 131, 2375-2384.

DOI: 10.1021/ja8087168

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60.    Donor-dictated Interlocking Co-complexation Reactions of LiNHDipp with Dimethylzinc: Synthesis and Structures of New Methyl(amido)zincates

W. Clegg, D. V. Graham, E. Herd, E. Hevia, A. R. Kennedy, M. D. McCall, L. Russo

Inorg. Chem. 2009, 48, 5320-5327.

DOI: 10.1021/ic900313b 

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59.    Direct lateral Metallation using Alkali-Metal-Mediated Zincation (AMMZn): SiC-H vs Si-O Bond Cleavage

E. Hevia, A. R. Kennedy, J. Klett, M. D. McCall

Chem. Commun. 2009, 3240-3242.

DOI: 10.1039/B903592C

 

58.    Synthetic and Structural Insights into the Zincation of Toluene: Direct Synergic Ring Metalation vs Indirect Non-synergic Lateral Metalation

D. R. Armstrong, J. García-Álvarez, D. V. Graham, G. W. Honeyman, E. Hevia, A. R. Kennedy, R. E. Mulvey

Chem. Eur. J, 2009, 15, 3800-3807.

DOI: 10.1002/chem.200801928

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57.    Contacted ion-pair lithium alkylamidoaluminates: intramolecular alumination (Al-H exchange) traps for TMEDA and PMDETA

B. Conway, J. García-Álvarez, E. Hevia, A. R. Kennedy, R. E. Mulvey, S. D. Robertson

Organometallics, 2009, 28, 6462-6468.

DOI: 10.1021/om900736a

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56.    Synergic Synthesis of Benzannulated Zincabicyclic Complexes, -Zincated N Ylides, through Sodium TMEDA-Mediated Zincation of a Haloarene

D. R. Armstrong, L. Balloch, W. Clegg, S. H. Dale, P. García-Álvarez, E. Hevia, L. M. Hogg, A. R. Kennedy, R. E. Mulvey, C. T. O’Hara

Angew. Chem. Int. Ed. 2009, 48, 8675-8678.

DOI: 10.1002/anie.200904506 

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55.    Structurally Defined Potassium-Mediated Zincation of Pyridine and 4-R-Substituted Pyridines (R=Et, iPr, tBu, Ph and Me2N) by Using Dialkyl-TMP-Zincate Bases

W. Clegg, B. Conway, D. V. Graham, E. Hevia, A. R. Kennedy, R. E. Mulvey, L. Russo, D. S. Wright

Chem. Eur. J. 2009, 15, 7074-7082.

DOI: 10.1002/chem.200900549 

 

2008

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54.    Synthesis and Structural Elucidation of Alkyl, Amido and Mixed Alkyl-Amido “Highly-Coordinated” Zincates

D. R. Armstrong, C. Dougan, D. V. Graham, E. Hevia, A. R. Kennedy

Organometallics, 2008, 27, 6063-6070.

DOI: 10.1021/om800786n

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53.    Metalation of 2, 4, 6-Trimethylacetophenone using Organozinc Reagents

D. R. Armstrong, A. M. Drummond, L. Balloch, D. V. Graham, E. Hevia, A. R. Kennedy

Organometallics, 2008, 27, 5860-5866.

DOI: 10.1021/om800658s

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52.    Synthesis and Structural Elucidation of Solvent-Free and Solvated Lithium Dimethyl(HMDS)zincates

D. R. Armstrong, E. Herd, D.V. Graham, E. Hevia,  A. R. Kennedy, W. Clegg, L. Russo

Dalton Trans. 2008, 1323-1330.

DOI: 10.1039/B716494G 

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51.    Transamination Chemistry of Sodium TMP-zincate: Synthesis and Crystal Structure of a Chiral Amidozincate

D. R. Armstrong, W. Clegg, S. H. Dale, J. García-Álvarez, R. W. Harrington, E. Hevia, G. W. Honeyman, A. R. Kennedy, R. E. Mulvey, C. T. O’Hara

Chem. Commun. 2008, 187-189.

DOI: 10.1039/B713987J 

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50.    Unmasking Representative Structures of TMP-Active Hauser and Turbo Hauser Bases

P. García-Álvarez, D. V. Graham, E. Hevia, A. R. Kennedy, J. Klett, R. E. Mulvey, C. T. O’Hara, S. Weatherstone

Angew. Chem. Int. Ed. 2008, 47, 8079-8081.

DOI: 10.1002/anie.200802618 

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49.    Synthesis, Structural Authentication, and Structurally Defined Metalation Reactions of Lithium and Sodium DA-Zincate Bases (DA= diisopropylamide) with Phenylacetylene

W. Clegg, J. García-Álvarez, P. García-Álvarez, D. V. Graham, R. W. Harrington, E. Hevia, A. R. Kennedy, R. E. Mulvey, L. Russo

Organometallics. 2008, 27, 2654-2663.

DOI: 10.1021/om8001813

​

48.    Structurally-defined Potassium-Mediated Regioselective Zincation of Amino-and Alkoxy Substituted Pyridines

B. Conway, D. V. Graham, E. Hevia, A. R. Kennedy, J. Klett, R. E. Mulvey

Chem. Commun. 2008, 2638-2640.

DOI: 10.1039/B805606D 

​

47.    Synthesis and Characterisation of New Bimetallic Alkali Metal-Magnesium Mixed Diisopropylamide-Acetylides: Structural Variations in Bimetallic Lithium- and Sodium-Heteroleptic Magnesiates

J. García-Álvarez, D. V. Graham, E. Hevia, A. R. Kennedy, R. E. Mulvey

Dalton Trans. 2008, 1481-1486.

DOI: 10.1039/B716215D 

​

46.    Alkali-Metal-Mediated Manganation(II) of Functionalized Arenes and Applications of Ortho-Manganated Products in Pd-Catalyzed Cross-Coupling Reactions with Iodobenzene

V. L. Blair, W. Clegg, B. Conway, E. Hevia, A. Kennedy, J. Klett, R. E. Mulvey, L. Russo

Chem. Eur. J. 2008, 14, 65-72.

DOI: 10.1002/chem.200701597

​

45.    Structurally-Defined Reactions of Sodium TMP-Zincate with Nitrile Compounds:  Synthesis of a Salt-like Sodium Sodiumdizincate and Other Unexpected Ion Pair Products

W. Clegg, S. H. Dale, E. Hevia, L. M. Hogg, G. W. Honeyman, R. E. Mulvey, C. T. O’Hara, L. Russo

Angew. Chem. Int. Ed. 2008, 47, 731-734.

DOI: 10.1002/anie.200704341

​

2007

 

44.    Structurally-Defined Direct C-Magnesiation and C-Zincation of N-Heterocyclic Aromatic Compounds using Alkali-Metal-Mediated Metallation

B. Conway, E. Hevia, A. R. Kennedy, R. E. Mulvey

Chem. Commun. 2007, 2864-2866.

DOI: 10.1039/B704362G 

​

43.    Isolation and structural elucidation of a key aluminoaromatic intermediate and evidence for dismutation phenomena in TMP-alumination chemistry

B. Conway, E. Hevia, J. García-Álvarez, D. V. Graham, A. R. Kennedy, R. E. Mulvey

Chem. Commun. 2007, 5241-5243.

DOI: 10.1039/B713913F 

​

42.    Lewis base stabilized lithium TMP – aluminates: an unexpected fragmentation and capture reaction involving cyclic ether 1,4-dioxane

J. Garcia-Alvarez, E. Hevia, A. R. Kennedy, J. Klett, R. E. Mulvey

Chem. Commun. 2007, 2402-2404.

DOI: 10.1039/B700785J

​

41.    Synthesis of Mixed Alkali Metal-Zinc Enolate Complexes Derived from 2, 4, 6-Trimethylacetophenone: New Inverse Crown Structures

S. H. Baillie, E. Hevia, A. R. Kennedy, R. E. Mulvey

Organometallics, 2007, 26, 204-209.

DOI: 10.1021/om060878k 

​

40.    Structural Variations in Bimetallic Sodium-Magnesium and Sodium-Zinc Ketimides, and a Sodium-Zinc Alkide-Alkoxide-Amide: Connections to Ring-Stacking, Ring-Laddering, and Inverse Crown Concepts

W. Clegg, S. H. Dale, D. V. Graham, R. W. Harrington, E. Hevia, L. M. Hogg, A. R. Kennedy, R. E. Mulvey

Chem. Commun. 2007, 1641-1643.

DOI: 10.1039/B618609B    

​

39.    Dizincation and Dimagnesiation of Benzene using Alkali-Metal-Mediated Metallation

D. R. Armstrong, W. Clegg, S. H. Dale, D. V. Graham, E. Hevia, L. M. Hogg, G. W. Honeyman, A. R. Kennedy, R. E. Mulvey

Chem. Commun. 2007, 598-600.

DOI: 10.1039/B613655A    

​

2006

 

38.    Lithium Dimethyl-amidozinc Complexes: Contrasting Zincate (Amido = TMP) and Inverse Zincate (Amido = HMDS) Structures on Addition of TMEDA

D. V. Graham, E. Hevia, A.R. Kennedy, R. E. Mulvey

Organometallics, 2006, 25, 3297-3300.

DOI: 10.1021/om060334i

​

37.    Synthesis and Reactivity of New(Methoxy)methyl Complexes of Manganese(I) and Rhenium(I)

E. Hevia, D. Miguel, J. Pérez, V. Riera

Organometallics, 2006, 25, 4909-4912.

DOI: 10.1021/om060459n

 

36.    Synergic Para-Directed-Monometalation of Bis(toluene)chromium by using Alkali-Metal-Mediated Magnesiation

P. C. Andrikopoulos, D. R. Armstrong, E. Hevia, A. R. Kennedy, R. E. Mulvey

Organometallics, 2006, 25, 2415-2418.

DOI: 10.1021/om060216v 

​

35.    Synthesis and Characterization of New Mixed-Metal Sodium-Magnesium Enolates Derived from 2,4, 6-Trimethylacetophenone

E. Hevia, K. W. Henderson, A. R. Kennedy, R. E. Mulvey

Organometallics, 2006, 25, 1778-1785.

DOI: 10.1021/om051076c 

​

34.    Electronic Structure and Excited States of Rhenium(I) Amido and Phosphido Carbonyl-Bipyridine Complexes Studied by Picosecond Time-Resolved IR Spectroscopy and DFT Calculations

A. Grabrielsson, M. Busby, P. Matousek, MI. Towrie, E. Hevia, L. Cuesta, J. Perez, S. Zalis, A. Vlcek, Jr

Inorg. Chem. 2006, 45, 9789-9797.

DOI: 10.1021/ic0614768

​

33.    Alkali-Metal-Mediated Zincation of Polycyclic Aromatic Hydrocarbons: Synthesis and Structures of Monozincated and Dizincated Naphthalenes

W. Clegg, S. H. Dale, E. Hevia, L. M: Hogg, G. W. Honeyman, R. E. Mulvey, C. T. O´Hara

Angew. Chem. Int. Ed. 2006, 45, 6548-6550.

DOI: 10.1002/anie.200602288

​

32.    Alkali-Metal-Mediated Zincation of Anisole: Synthesis and Structures of Three Instructive Ortho-Zincated Complexes

W. Clegg, S. H. Dale, E. Hevia, G. W. Honeyman, R. E. Mulvey

J. Am. Chem. Soc. 2006, 128, 7434-7435.

DOI: 10.1021/ja061898g

​

31.    Directed Meta-Metalation Using Alkali-Metal-Mediated Zincation

D. R. Armstrong, W. Clegg, S. H. Dale, E. Hevia, L. M. Hogg, G. W. Honeyman, R. E. Mulvey

Angew. Chem. Int. Ed. 2006, 45, 3775-3778.

DOI: 10.1002/anie.200600720

 

30.    Reactivity of Molybdenum and Rhenium Hydroxo Complexes toward Organic Electrophiles: Reactions that Afford Carboxylato Products

L. Cuesta, E. Hevia, D. Morales, J. Pérez, L. Riera, D. Miguel

Organometallics, 2006, 25, 1717-1722.

DOI: 10.1021/om051081g

​

29.    Pre-Metalation Insights into the Use of Alkali-Metal-Mediated Zincation for Directed ortho Metalation of a Tertiary Aromatic Amide

W. Clegg, S. H. Dale, E. Hevia, G. W. Honeyman, R. E. Mulvey

Angew. Chem. Int. Ed. 2006, 45, 2370-2374.

DOI: 10.1002/anie.200503202

​

28.    Post-Metalation Insights into the Use of Alkali-Metal-Mediated Zincation for Directed ortho-Metalation of a Tertiary Aromatic Amide

W. Clegg, S. H. Dale, R. W. Harrington, E. Hevia, G. W. Honeyman, R. E. Mulvey

Angew. Chem. Int. Ed. 2006, 45, 2374-2377.

DOI: 10.1002/anie.200503213

​

27.    Building an Extended Inverse Crown Motif via Alkali-Metal-Mediated -Magnesation of Furan

D. V. Graham, E. Hevia, A. R. Kennedy, R. E. Mulvey, C. T. O’Hara, Christine Talmard

Chem. Commun. 2006, 417.

DOI: 10.1039/B514985A 

​

2005

 

26.    Trapping, Stabilization, and Characterization of an Enolate Anion of a 1, 6 – Adduct of Benzophenone Chelated by a Sodium Alkylamidozincate Cation

E. Hevia, G. W. Honeyman, A. R. Kennedy, R. E. Mulvey

J. Am. Chem. Soc. 2005, 127, 13106-13107.

DOI: 10.1021/ja053756c

 

25.    Alkali-Metal–Mediated Zincation of Ferrocene: Synthesis, Structure, and Reactivity of a New Lithium TMP-Zincate Reagent

H. R. L. Barley, William Clegg, S. H. Dale, E. Hevia, G. W. Honeyman, A. R. Kennedy, R. E. Mulvey

Angew. Chem. Int. Ed., 2005, 44, 6018-6021.

DOI: 10.1002/anie.200501560

​

24.    Stoichiometrically-controlled reactivity and supramolecular storage of butylmagnesiate anions

P. C. Andrikopoulos, D. R. Armstrong, E. Hevia, A. R. Kennedy, R. E. Mulvey, C. T. O’Hara

Chem. Commun. 2005, 1131-1133.

DOI: 10.1039/B416636A

​

23.    Sodium Dialkyl-amidozincates, Alkyl or Amido Bases? An Experimental and Theoretical Case Study

P. C. Andrikopoulos, D. R. Armstrong, H. R. L. Barley, W. Clegg, S. H. Dale, E. Hevia, G. W. Honeyman, A. R. Kennedy, R. E. Mulvey

J. Am. Chem. Soc. 2005, 127, 6184-6186.

DOI: 10.1021/ja050860l

​

22.    Selective Meta-Deprotonation of Toluene Using Alkali Metal-Mediated Magnesiation.

P. C. Andrikopoulos, D. R. Armstrong, D. V. Graham, E. Hevia, A. R. Kennedy, R. E. Mulvey, C. T. O’Hara, C. Talmard

Angew. Chem. Int. Ed. 2005, 44, 3459-3462.

DOI: 10.1002/anie.200500379 

 

21.    Synthesis and characterization of a series of alkylmagnesium amide and related oxygen-contaminated alkoxy compounds

B. Conway, E. Hevia, A. R. Kennedy, R. E. Mulvey, S. Weatherstone

Dalton Trans. 2005, 1532-1544.

DOI: 10.1039/B501502B 

​

20.    Activation of ancillary ligands in the reactions of DMAD with phosphido and alkylidenamido rhenium complexes

L. Cuesta, E. Hevia, D. Morales, J. Pérez, V. Riera, M. Seitz, D. Miguel

Organometallics 2005, 24, 1772-1775.

DOI: 10.1021/om049019r

​

19.    Activation of a 1,10-phenanthroline ligand on a rhenium tricarbonyl complex

L. Cuesta, E. Hevia, D. Morales, J. Pérez, V. Riera, E. Rodríguez, D. Miguel

Chem. Commun. 2005, 116-117.

DOI: 10.1039/B412447B 

 

18.    Synergic monodeprotonation of bis(benzene)chromium using mixed alkali metal-magnesium amide bases and structural characterization of the heterotrimetallic products

E. Hevia, G. W. Honeyman, A. R. Kennedy, R. E. Mulvey, D. C. Sherrington

Angew. Chem. Int. Ed. 2005, 44, 68-72.

DOI: 10.1002/anie.200460637 

​

2004

 

17.    Isolation and characterization of the heterometallic sodium-magnesium mixed monoalkyl-bisamido complex [Na(-Bu)(-TMP)Mg(TMP).(TMEDA)]: chelate-trapping of a surprising intermediate in the formation of  inverse crowns

E. Hevia, D. J. Gallagher, A. R. Kennedy, R. E. Mulvey, C. T. O’Hara, C. Talmard

Chem. Commun. 2004, 2422-2423.

DOI: 10.1039/B410293B 

 

16.    A homologous series of regioselectively tetradeprotonated group 8 metallocenes: new inverse crown ring compounds synthesized via mixed sodium-magnesium tris(diisopropylamide) synergic     base

P. C. Andrikopoulos, D.  R. Armstrong, W. Clegg, C. J. Gilfillan, E. Hevia, A. R. Kennedy, R. E. Mulvey, C. T.     O’Hara, J.  A. Parkinson, D. M. Tooke

J. Am. Chem. Soc. 2004, 126, 11612-11620.

DOI: 10.1021/ja0472230 

​

15.    Synthesis and crystal structure of [{nBuMg(-TMP)2}] and of a homometallic inverse crown in tetranuclear [{nBuMg2[-N(H)Dipp]2(3-OnBu)}2]

E. Hevia, A. R. Kennedy, R. E. Mulvey, S. Weatherstone

Angew. Chem. Chem. Int. Ed. 2004, 43, 1709-1712.

DOI: 10.1002/anie.200353286

​

14.    Reactivity of Molybdenum and Rhenium hydroxo-carbonyl complexes toward organic electrophiles

L. Cuesta, D. C. Gerbino, E. Hevia,  D. Morales, M. E. Navarro Clemente, J. Pérez, L. Riera, V. Riera, D. Miguel, I. Del Rio, S. Garcia-Granda

Chem. Eur. J. 2004, 10, 1765-1777.

DOI: 10.1002/chem.200305577

 

2003

​

13.    Solvent-free and TMEDA-solvated mixed alkali metal-magnesium tris-diisopropylamides

E. Hevia, F. R. Kenley, A. R. Kennedy, R. E. Mulvey, R. B. Rowlings

Eur. J. Inorg. Chem. 2003, 3347-3353.

DOI:  10.1002/ejic.200300413 

 

12.    Synthesis of -lactams from a N-rhenaimine: effect of the transition metal on the energetic profile of the Staudinger reaction

E. Hevia, J. Pérez, V. Riera, D. Miguel, M. I. Menéndez, T. L. Sordo, S. García-Granda

J. Am. Chem. Soc. 2003, 125, 3706-3707.

DOI: 10.1021/ja034070s

​

11.    Mono and dimetallic cyanocomplexes with {Mo(3-allyl)(CO)2(N-N)} fragments

J. Pérez, E. Hevia, L. Riera, V. Riera, S. García-Granda, E. García-Rodríguez, D. Miguel

Eur. J. Inorg. Chem. 2003, 1113-1120.

DOI: 10.1002/ejic.200390142

​

10.    A new reactivity pattern of low-valent transition-metal hydroxo complexes: straightforward synthesis of hydrosulfido complexes via reaction with carbon disulfide

D. Gerbino, E. Hevia, D. Morales, M. E. Navarro Clemente, J. Pérez, L. Riera, V. Riera, D. Miguel

Chem. Commun. 2003, 328-329.

DOI: 10.1039/B210860G

​

9.    Reactivity of the amido complex [Re(NHpTol)(CO)3(bipy)] toward neutral organic electrophiles

E. Hevia, J. Pérez, V. Riera, D. Miguel

Organometallics 2003, 22, 257-263.

DOI: 10.1021/om020667p

 

2002

​

8.    Manganese (I) and rhenium (I) tricarbonyl (alkylthio)methyl and alkylidenesulfonium complexes

E. Hevia, J. Pérez, V. Riera, D. Miguel

Organometallics 2002, 21, 5312-5319.

DOI: 10.1021/om020522i 

 

7.    Insertion and cycloaddition reactivity of a transition-metal N-metalloimine

E. Hevia, J. Pérez, V. Riera, D. Miguel

Angew. Chem. Int. Ed. 2002, 41, 3858-3860.

DOI: 10.1002/1521-3773

 

6.    Insertion of Unsaturated Organic Electrophiles into Molybdenum-Alkoxide and Rhenium-Alkoxide Bonds of Neutral, Stable Carbonyl Complexes

E. Hevia, J. Pérez, L. Riera,  V. Riera, I. Del Río, S. García-Granda, D. Miguel

Chem. Eur. J. 2002, 8, 4510-4521.

DOI: 10.1002/1521-3765

 

5.    Different sites of insertion in the reaction of isocyanates with [Re(N(R)Ar)(CO)3(bipy)] (R = H or Me): N-H vs. Re-N

E. Hevia, J. Pérez, V. Riera, D. Miguel

Chem. Comun. 2002, 1814-1815.

DOI: 10.1039/B203261A  

 

4.    New synthetic routes to cationic rhenium tricarbonyl bipyridine complexes with labile ligands

E. Hevia, J. Pérez, V. Riera, D. Miguel, S. Kassel, A. Rheingold

Inorg. Chem. 2002, 41, 4673-4679.

DOI: 10.1021/ic020174c  

​

3.    New octahedral rhenium (I) tricarbonyl amido complexes

E. Hevia, J. Pérez,  V. Riera, D. Miguel

Organometallics 2002, 21, 1966-1974.

DOI: 10.1021/om0110383

​

2.    Reactive Alkoxide Complexes of Groups 6 and 7 Metals

E. Hevia, J. Pérez, L. Riera, V. Riera, D. Miguel

Organometallics 2002, 21, 1750-1752.

DOI: 10.1021/om010977s 

​

2001

​

1.    Synthesis and structure of a tris imido phosphonate anion; the missing link in imido analogues of phosphorus oxoanions

L. T. Burke, E. Hevia-Freire, R. Holland, J. C. Jeffery, A. P. Leedham, C. A. Russell, A. Steiner, A. Zagorski

Chem. Comun. 2000, 1769-1770.

DOI: 10.1039/B004192K

Eva Hevia Group, Department of Pure and Applied Chemistry, WestCHEM, University of Strathclyde, 

295 Cathedral Street, Glasgow, G1 1XL, UK